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butalbital will minimize the extent or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.cenobamate will enhance the stage or impact of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Check Carefully. Take into account a dose reduction of CYP2C19 substrates, as clinically ideal, w